Description |
Noggin, Human |
Source |
E.Coli |
AAs Sequence |
206 amino acid polypeptide chains |
MW |
46.2 kDa |
Formulation |
Lyophilized from a 0.2μm filtered solution in 30% CH3CN, 0.1% TFA. |
Purity |
Greater than 95% as determined by SDS-PAGE |
Endotoxin Level |
N/A |
Biological Activity (ED50) |
The ED50 was determined by its ability to inhibit 5.0 ng/ml of BMP-4 induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED50 for this effect is 0.05-0.08 µg/ml of Noggin, corresponding to a Specific Activity of 12,500-20,000units/mg |
Citation |
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